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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
9.09
Human Site:
T520
Identified Species:
15.38
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T520
A
T
A
S
P
P
T
T
A
G
S
N
N
P
C
Chimpanzee
Pan troglodytes
XP_509441
819
90122
T490
Q
P
Q
A
V
I
M
T
S
G
P
L
K
R
E
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
D83
D
F
G
P
R
S
I
D
P
T
L
T
R
L
F
Dog
Lupus familis
XP_546925
857
93734
T525
A
T
A
N
S
T
A
T
A
G
G
S
N
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
R532
P
T
A
T
A
T
A
R
D
N
N
P
C
L
T
Rat
Rattus norvegicus
Q6AXT8
471
49872
R164
Q
R
I
E
P
P
D
R
R
W
Q
Y
L
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
T564
T
V
P
N
A
C
L
T
Q
L
L
A
T
A
K
Frog
Xenopus laevis
NP_001084764
548
60887
M241
E
E
E
P
L
L
D
M
E
M
L
M
A
E
I
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
R495
P
I
S
S
K
K
S
R
H
S
Q
R
P
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
T499
S
D
P
M
L
N
S
T
L
A
Q
L
L
T
S
Honey Bee
Apis mellifera
XP_394429
1014
115124
N681
T
M
N
M
P
A
D
N
I
M
P
T
V
N
Q
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
F582
S
A
D
N
G
F
L
F
G
G
N
N
T
P
G
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T982
S
E
I
G
K
T
S
T
S
S
S
S
T
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S752
N
G
I
S
A
M
K
S
S
P
P
A
P
P
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
13.3
0
60
N.A.
13.3
13.3
N.A.
N.A.
6.6
0
6.6
N.A.
6.6
6.6
20
13.3
P-Site Similarity:
100
26.6
0
73.3
N.A.
26.6
13.3
N.A.
N.A.
13.3
0
20
N.A.
20
6.6
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
22
8
22
8
15
0
15
8
0
15
8
15
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
15
% C
% Asp:
8
8
8
0
0
0
22
8
8
0
0
0
0
0
0
% D
% Glu:
8
15
8
8
0
0
0
0
8
0
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
8
8
0
0
0
8
29
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
22
0
0
8
8
0
8
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
15
8
8
0
0
0
0
0
8
0
8
% K
% Leu:
0
0
0
0
15
8
15
0
8
8
22
15
15
22
8
% L
% Met:
0
8
0
15
0
8
8
8
0
15
0
8
0
0
8
% M
% Asn:
8
0
8
22
0
8
0
8
0
8
15
15
15
8
0
% N
% Pro:
15
8
15
15
22
15
0
0
8
8
22
8
15
29
0
% P
% Gln:
15
0
8
0
0
0
0
0
8
0
22
0
0
0
8
% Q
% Arg:
0
8
0
0
8
0
0
22
8
0
0
8
8
8
0
% R
% Ser:
22
0
8
22
8
8
22
8
22
15
15
15
0
0
8
% S
% Thr:
15
22
0
8
0
22
8
43
0
8
0
15
22
8
8
% T
% Val:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _